An Introduction to N-of-1 Trial Design and Conduct in Health Research

Organised by the HRB-TMRN, this workshop will introduce participants to the design and conduct of N-of-1 trials in health research. The workshop will be delivered in three parts:

Part 1: Introduce participants to the reasons for which N-of-1 trials are conducted and contemporary examples of their use in informing clinical decision-making.

Part 2: Introduce participants to the range of designs available within the suite of N-of-1 methods. The strengths and weaknesses of these designs will be discussed and issues related to the analysis of data produced by these designs will be introduced. Reporting guidelines for N-of-1 trials will also be presented.

Part 3: Focus on the practicalities of data collection during N-of-1 trials. These trials usually require intensive longitudinal measurement of outcomes within individuals. Strategies such as daily diaries, online surveys and smartphone-delivered experience sampling will be discussed. The workshop will conclude with a group discussion on opportunities to apply N-of-1 methods within health research in Ireland and whether further training opportunities would be useful.

The workshop will be delivered by Dr. Suzanne McDonald (Institute of Health and Society, Newcastle University, UK; Centre for Clinical Research, University of Queensland, AUS).

Dr McDonald is a Research Methodologist and is interested in the development and application of N-of-1 methods (also known as ‘single-case methods’) in psychology and medicine. Suzanne is co-chair of the International Collaborative Network for N-of-1 Clinical Trials and Single-Case Experimental Designs and co-chair of the UK Network for N-of-1 Methods. Suzanne is also a Chartered Psychologist with the British Psychological Society (BPS) and a registered Practitioner Psychologist with the Health Care and Professions Council (HCPC).

Click here for more details and to register.